Faculty Mentor(s)
Dr. Jeffrey Johnson, Chemistry
Document Type
Poster
Event Date
4-12-2024
Abstract
Reactions involving carbon-carbon bond activation are of interest to develop methods of functionalizing molecules. Work in the Johnson Group utilizes rhodium-catalyzed decarbonylation to form new carbon-carbon bonds in pyridyl ketones, where the nitrogen on the pyridine ring acts as a directing group. Though this reaction is easily replicated and gives high yields, the need for a pyridine directing group limits the range of molecules that can be synthesized. To broaden the scope of this reaction, novel directing group compounds were synthesized through different routes and their efficacy in the decarbonylation reaction was explored.
Recommended Citation
Repository citation: Forrest, Bryan J.; Klanseck, Isabelle M.; Aguilar-Romero, Jazmin E.; and Kapitula, Mary G., "Exploring the Effectiveness of Directing Groups for Rhodium-catalyzed Decarbonylation" (2024). 23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2024). Paper 28.
https://digitalcommons.hope.edu/curca_23/28
April 12, 2024. Copyright © 2024 Hope College, Holland, Michigan.
Comments
This work was supported by the Arnold and Mabel Beckman Foundation, the Dow Foundation, the Schaap Science Undergraduate Research Fund and by the National Science Foundation under Grant No. 1764118.
Additional authors appear on poster that are not listed in the abstract booklet: Jazmin E. Aguilar-Romero and Mary G. Kapitula.