Adsorption and breakdown of penicillin antibiotic in the presence of titanium oxide nanoparticles in water
Document Type
Article
Publication Date
5-2012
Publication Source
Chemosphere
Volume Number
87
Issue Number
8
First Page
911
Last Page
917
Publisher
Pergamon-Elsevier Science Ltd
ISSN
0045-6535
Abstract
The fate and transport of antibiotics in natural water systems is controlled in part by interactions with nanometer (10(-9) m) metal oxide particles. Experiments were performed by mixing solutions of ampicillin (AMP), a common, penicillin-class human and veterinary antibiotic, with 25 nm-TiO2 (anatase) nanoparticles at different pH conditions. Both sorption and degradation of AMP were observed in the AMP-nanoparticle solutions. For AMP concentrations from similar to 3 mu M to 2.9 mM the overall AMP removal from solution can be described by linear isotherms with removal coefficients (K-r) of 3028 (+/- 267) L kg(-1) at pH 2, 11,533 (+/- 823) L kg(-1) at pH 4, 12,712 (+/- 672) L kg(-1) at pH 6, and 1941 (+/- 342) L kg(-1) at pH 8. Mass spectral analysis of AMP solutions after removal of the solid nanoparticles yielded ions that indicate the presence of peniclloic acid, penilloic acid and related de-ammoniated by-products as possible compounds resulting from the degradation of AMP at the TiO2 surface.
Recommended Citation
Peterson, Jonathan W., Laura J. Petrasky, Michael D. Seymour, Rachel S. Burkhart and Amanda B. Schuiling. "Adsorption and Breakdown of Penicillin Antibiotic in the Presence of Titanium Oxide Nanoparticles in Water." Chemosphere 87, no. 8.00 (2012): 911-917.
