A new accelerator Mass Spectrometry System for ¹⁴C-quantification of Biochemical Samples

Authors

• Ted J. Ognibene, Lawrence Livermore National Laboratory, Center for Accelerator Mass Spectrometry
• Graham Bench, Lawrence Livermore National Laboratory, Center for Accelerator Mass Spectrometry
• Tom A. Brown, Lawrence Livermore National Laboratory, Center for Accelerator Mass Spectrometry
• Graham F. Peaslee, Lawrence Livermore National Laboratory, Center for Accelerator Mass SpectrometryFollow
• John S. Vogel, Lawrence Livermore National Laboratory, Center for Accelerator Mass Spectrometry

Document Type

Article

Publication Date

7-15-2002

Publication Source

International Journal of Mass Spectrometry

Volume Number

218

Issue Number

3

First Page

255

Last Page

264

Publisher

Elsevier

Abstract

A compact accelerator mass spectrometry (AMS) system that meets our requirements for View the MathML source-quantification of biochemical samples is described. The spectrometer occupies approximately 5 m2 of floor space and can measure >300 samples per day with 3% precision. A long diffuse gas cell is used to destroy interfering molecules and to charge exchange injected negative ions. System sensitivity is < 1 amol View the MathML source/mg carbon on milligram-sized samples with a dynamic range that extends over 4 orders magnitude. All components, with the exception of the ion source, are commercially available and the system operates reliably with low maintenance.

Recommended Citation

Published in: International Journal of Mass Spectrometry, Volume 218, Issue 3, July 15, 2002, pages 255-264. Copyright © 2002 Elsevier.