A new accelerator Mass Spectrometry System for 14C-quantification of Biochemical Samples

Document Type

Article

Publication Date

7-15-2002

Publication Source

International Journal of Mass Spectrometry

Volume Number

218

Issue Number

3

First Page

255

Last Page

264

Publisher

Elsevier

Abstract

A compact accelerator mass spectrometry (AMS) system that meets our requirements for View the MathML source-quantification of biochemical samples is described. The spectrometer occupies approximately 5 m2 of floor space and can measure >300 samples per day with 3% precision. A long diffuse gas cell is used to destroy interfering molecules and to charge exchange injected negative ions. System sensitivity is <1 amol View the MathML source/mg carbon on milligram-sized samples with a dynamic range that extends over 4 orders magnitude. All components, with the exception of the ion source, are commercially available and the system operates reliably with low maintenance.

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