Faculty Mentor(s)

Dr. Jeffrey Johnson, Chemistry

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The kinetics involved in the reaction pathways of transition metal-catalyzed carbon-carbon bond activation reactions can provide key insights into the mechanism. Previous work has shown that pyridyl ketones undergo rhodium-catalyzed decarbonylation reactions. The determination of the mechanistic pathway of this reaction could allow for the knowledge necessary for exploring alternative reactivity. Utilizing in situ Fourier Transform Infrared Spectroscopy (FTIR) and Nuclear Magnetic Resonance Spectroscopy (NMR), kinetic analysis of the decarbonylation reaction is being performed with various substituted pyridyl ketones. Initial rate constants will be used to compare the electronic effects of substituents, providing insight of the intermediates involved.


This material is based upon work supported by the National Science Foundation under Grant Nos. 1148719 and 1764118. This work was additionally supported by the Dow Scholars Program, and the Schaap Endowed Fund for Undergraduate Research.

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