Faculty Mentor(s)
Dr. Jeffrey Johnson, Chemistry
Document Type
Poster
Event Date
4-17-2026
Abstract
For years, the Suzuki-Miyaura reaction has served as an effective method of coupling various carbon-carbon structures, typically of aryl halides with aryl boronic acids. However, the Suzuki reaction is not without limitations, specifically with ortho-fluorinated aryl and heterocyclic boron compounds. The palladium catalyzed cross coupling reaction of tertiary alcohols with halides has shown potential in succeeding where the Suzuki reaction is limited. This research aims at exploring the extent of effectiveness in the use of tertiary alcohols in palladium catalyzed coupling reactions. Specifically, this work focuses on the change in reactivity depending on the aryl halide used.
Recommended Citation
Repository citation: D'Amico, Joseph E.; Frederick, Annabelle G.; and Corey, Nicholas S., "Palladium-Catalyzed Coupling of Aryl Halides to Organometallics from Tertiary Alcohols" (2026). 25th Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2026). Paper 8.
https://digitalcommons.hope.edu/curca_25/8
April 17, 2026. Copyright © 2026 Hope College, Holland, Michigan.
Comments
This work was supported by the Hope College Department of Chemistry, the Schaap Endowed Fund for Undergraduate Research and by the donors of ACS Petroleum Research Fund under Undergraduate Research Grant 67565-UR1 (J.J. served as Principal Investigator on ACS PRF 67565-UR1).
One author's name appears differently on poster than the abstract booklet: Nick S. Corey.