Feasibility of Isotope Harvesting at a Projectile Fragmentation Facility: Cu-67

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The work presented here describes a proof-of-principle experiment for the chemical extraction of Cu-67 from an aqueous beam stop at the National Superconducting Cyclotron Laboratory (NSCL). A 76 MeV/A Cu-67 beam was stopped in water, successfully isolated from the aqueous solution through a series of chemical separations involving a chelating disk and anion exchange chromatography, then bound to NOTA-conjugated Herceptin antibodies, and the bound activity was validated using instant thin-layer chromatography (ITLC). The chemical extraction efficiency was found to be 88 +/- 3% and the radiochemical yield was >= 95%. These results show that extraction of radioisotopes from an aqueous projectile-fragment beam dump is a feasible method for obtaining radiochemically pure isotopes.