Dr. Jeffrey Johnson, Chemistry
Carbon-carbon single bond activation and functionalization occurs in a quinolinyl ketone structure through rhodium catalyzed bond activation and subsequent insertion of a Michael acceptor, primarily methyl acrylate and N,N-dimethylacrylamide. A variety of quinolinyl ketones and Michael acceptors are observed to react catalytically, forming a disubstituted alkene coupling product. A broad scope of quinolinyl ketones and Michael acceptors have been used to investigate the mechanism for the reaction.
Repository citation: Jansen, Jacob; Reed, Katherine; Dyke, Gabriella; Trentadue, Kathryn; Gregerson, Caroline; Otteman, Christian; Stachowski, Jessica; Kirsch, Janelle; and Phipps, Erik, "Carbon-Carbon Single Bond Activation Used for Coupling with Michael Acceptors" (2017). 16th Annual Celebration of Undergraduate Research and Creative Performance (2017). Paper 78.
April 21, 2017. Copyright © 2017 Hope College, Holland, Michigan.