Dr. Jeffrey Johnson
Previous research established that the decarbonylative nickel-mediated cross coupling reaction of N-substituted cyclic imides with diorganozinc reagents is possible with a range of phthalimide substitution and diorganozinc reagents. Current investigation into this reaction demonstrates that electron deficient N-aryl substitutions promote more catalyst turnovers than the previous work suggested.
All of the previous reactions utilized N-substituted phthalimides. Reaction development is underway to expand the scope of this reaction to imides with saturated backbones. Further studies to investigate the effect the saturated backbone have been performed via NMR and in situ IR.
Repository citation: Fodor, Sarah, "Investigating The Decarbonylation of Cyclic Imides Using a Nickel Catalyst" (2014). 13th Annual Celebration of Undergraduate Research and Creative Performance (2014). Paper 26.
April 11, 2014. Copyright © 2014 Hope College, Holland, Michigan.