Exploring the Decarbonylation of Cyclic Imides Utilizing a Nickel Catalyst

Student Author(s)

Sarah Fodor

Faculty Mentor(s)

Dr. Jeffery Johnson

Document Type


Event Date



Previous research established that a decarbonylative nickel-mediated cross coupling reaction of N-substituted cyclic imides with diorganozinc reagents is possible with many different functional groups in the R position of the cyclic imide. The scope of the reaction was further expanded with a wide variety of diorganozinc reagents (R1). (J. Org. Chem., 2011, 76, 3588). All of the previous reactions were successful using an unsaturated backbone. The focus of this particular research is to expand scope of the reaction by exploring the possibility of a saturated imide backbone. To determine the ideal reaction conditions to promote the decarbonylation it was tried under a variety of solvents and ligands. (Original contains diagram)

This document is currently not available here.