The Use of Celebrex for Postoperative Total Knee Replacement Patients

Faculty Mentor(s)

Kristie Dennett, Holland Hospital
Dr. Nancy Barnum, Hope College

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Knee replacement surgeries are prevalent among the elderly population, and postoperative pain is still not being managed appropriately in many cases, leading to prolonged hospital stays and ineffective physical therapy and rehabilitation efforts. Celebrex (Celecoxib) is a nonsteroidal anti-inflammatory drug that has been shown to reduce pain and inflammation in osteoarthritis and postsurgical patients. The purpose of this research is to examine the effectiveness of Celebrex administration on reducing pain and improving range of motion in total knee replacement patients at a Midwest hospital. The conceptual framework for this study was Katharine Kolcaba, which focuses on providing the patient comfort, including pain relief, in order to facilitate holistic healing. This study is a quantitative, retrospective, cross-sectional, quasi-experimental study with a random sample of 30 patients in the control group, and 30 patients in the experimental group. The data was collected through chart review at the hospital. SPSS statistical software was used to examine frequencies and Pearson r correlations and to run independent t-tests. Results and conclusions are pending. Limitations of the study include having a small sample size, inconsistent medications and dosages given in addition to Celebrex, and subjective nature of pain reports. Implications for future study include modifying dosage of Celebrex and other pain medications given, using nursing care to proactively manage pain, and efficacy of alternative pain management techniques.

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